Evaluation of Anti-inflammatory Activity of Methanolic Extract of Solanum nigrum (Solanaceae)

نویسندگان

  • Gururaja Perumal Pazhani KRS Pallavan College of Pharmacy, Mannur - 602 105, Tamilnadu, India
  • Manickam Karunanithi Centre for Advanced Research in Indian System of Medicine, SASTRA University, Thanjavur, Tamilnadu, India
  • Natesan Subramanian Bharathidasan Institute of Technology, Anna University Tiruchrappalli, Tiruchirappalli - 620 024, Tamilnadu, India
  • Vellayutham Ravichandran School of Pharmaceutical Sciences Vels College of Pharmacy, Chennai- 600 035, Tamilnadu, India
چکیده مقاله:

      The methanolic extract of whole plants of Solanum nigrum L. was investigated for anti-inflammatory activity on the experimental animal models. The methanolic extract at a concentration of 100 mg.kg-1 and 200 mg.kg-1, p.o. showed the significant dose dependent anti-inflammatory activity in carrageenin and egg white induced hind paw oedema in rats. Anti-inflammatory activity of the tested extract was comparable with that of the standard drug indomethacin (10 mg.kg-1) and cyproheptadine (8 mg.kg-1). The results lend support to the traditional use of Solanum nigrum in the treatment of inflammatory diseases.

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منابع مشابه

evaluation of anti-inflammatory activity of methanolic extract of solanum nigrum (solanaceae)

the methanolic extract of whole plants of solanum nigrum l. was investigated for anti-inflammatory activity on the experimental animal models. the methanolic extract at a concentration of 100 mg.kg-1 and 200 mg.kg-1, p.o. showed the significant dose dependent anti-inflammatory activity in carrageenin and egg white induced hind paw oedema in rats. anti-inflammatory activity of the tested extract...

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عنوان ژورنال

دوره 5  شماره 3

صفحات  151- 156

تاریخ انتشار 2009-07-01

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